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Individual CardOut vs. 2 relationships for all subjects are shown in Fig. 2, top, with regression curves determined from overall mean values for regression coefficients in Fig. 2, bottom. Figure 3 shows mean regression curves from selected previous studies, largely using dye dilution techniques or direct Fick method to measure CardOut in both athletes and normal subjects. Our data lie in the low end of the range of most previous studies, although the present data closely match our own study using the direct Fick method to validate the open-circuit method used in this study.

Fig. 2.CardOut vs. 2. Each line represents 1 subject. Dashed and solid lines represent subjects with non-negative and significant negative quadratic term, respectively. Bottom: mean regression curves to compare groups. Open symbols, data from our previous validation study using direct Fick method; •, subjects with non-negative curvature term; ?, subjects with significant negative curvature.

Fig. 3.CardOut vs. 2 curves. Shown are mean regression curves to compare data from various sources. Open symbols, data from this study (circles) and our previous Fick validation study (squares); solid symbols, data from the literature. Sigue leyendo

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